Amodis 60-ml

Amodis 60-ml (200 mg) Suppository

SKU: M49259

GEN Name: Metronidazole
Per Pieces
29.89 BDT

Indication Duration Adult & Children Children of dosage over 10 years in days Trichomoniasis** 7 200 mg t.i.d. or 400 mg b.i.d. 100 mg t.i.d. 100 mg b.i.d. 50 mg t.i.d. 2 800 mg in the morning and - - - 1.2 gm at night 1 2.0 gm as a…

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Indication Duration Adult & Children Children of dosage over 10 years in days Trichomoniasis** 7 200 mg t.i.d. or 400 mg b.i.d. 100 mg t.i.d. 100 mg b.i.d. 50 mg t.i.d. 2 800 mg in the morning and - - - 1.2 gm at night 1 2.0 gm as a single dose - - - Invasive intestinal 5 800 mg t.i.d. 400 mg t.i.d. 200 mg q.i.d. 200 mg t.i.d. amoebiasis Extra intestinal 5-10 400 -800 mg t.i.d. 200 -400 mg t.i.d 100-200 mg q.i.d 100 -200 mg t.i.d amoebiasis (including liver abscess) and symptomless amoebic cyst passers Giardiasis 3 2.0 gm once daily 1.0 gm once daily 600-800 mg 500 mg once daily once daily Acute ulcerative gingivitis 3 200 mg t.i.d. 100 mg t.i.d. 100 mg b.i.d. 50 mg t.i.d. Acute dental infections 3 -7 200 mg t.i.d. - - - Bacterial vaginosis 5–7 400–500 mg twice daily - - - 1 2.0 gm as a single dose - - - Leg ulcers and 7 400 mg t.i.d. - - - pressure sores Anaerobic infections 7 Either 400 mg every 8 hours or 500 mg every 8 hours 7.5 mg/kg t.i.d. 7.5 mg/kg t.i.d 7.5 mg/kg t.i.d Surgical prophylaxis 7.5 mg/kg t.i.d. 7.5 mg/kg t.i.d. **Trichomoniasis: Concomitant treatment of sexual consorts is recommended. 7.5 mg/kg t.i.d. 7-10 years 3-7 years 1-3 years COMPOSITION Amodis® 400 Tablet : Each film coated tablet contains Metronidazole BP 400 mg. Amodis® 500 Tablet : Each film coated tablet contains Metronidazole BP 500 mg. Amodis® Suspension : Each 5 ml contains Benzoyl Metronidazole equivalent to Metronidazole BP 200 mg. PHARMACOLOGY Amodis® (Metronidazole), a nitroimidazole has an extremely broad spectrum antiprotozoal and antimicrobial activities, with high activity against anaerobic bacteria and protozoa. Amodis® (Metronidazole) is usually completely and rapidly absorbed after oral administration. The half-life in plasma is about 8 hours. About 10% of the drug is bound to plasma proteins. Amodis® (Metronidazole) penetrates well into body tissues and fluids. The liver is the main site of metabolism. Both unchanged Metronidazole and metabolites are excreted in various proportions in the urine after oral administration. INDICATION All forms of amoebiasis (intestinal and extra-intestinal disease including liver abscess and that of symptomless cyst passers) Trichomoniasis Giardiasis Bacterial vaginosis Acute ulcerative gingivitis Anaerobic infections including septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis etc. Anaerobically-infected leg ulcers and pressure sores Acute dental infections (e.g. acute pericoronitis and acute apical infections) Surgical prophylaxis (prevention of postoperative infections due to anaerobic bacteria, particularly species of bacteroides and anaerobic streptococci Chronic symptomatic peptic ulcer disease (as an agent of triple therapy to eradicate H. pylori-the most important aetiological factor of peptic ulcer) ADVERSE REACTION Metalic taste, furred tongue, nausea, vomiting, diarrhoea, drowsiness, rashes and mild reversible leucopenia may be observed during treatment. DRUG INTERACTION Metronidazole interacts with warfarin, nicoumalone, phenytoin, phenobarbitone, fluorouracil, disulfiram, lithium, cimetidine etc. PREGNANCY & LACTATION Not recommended during first & later trimesters. Breast feeding should be delayed until 48 hours after discontinuing metronidazole in the mother. STORAGE CONDITION Tablet: Store in a cool and dry place. Protect from light and moisture. Keep out of the reach of children. Suspension: Store in a cool and dry place. Protect from light. Keep out of the reach of children. HOW SUPPLIED Amodis® 400 Tablet : Box containing 200 tablets in blister pack. Amodis® 500 Tablet : Box containing 100 tablets in blister pack. Amodis® Suspension : Each PET bottle contains 60 ml suspension with measuring cup. ® Registered Trade Mark. Revision No.: 03 Manufactured by : Amodis ® Metronidazole BP Amodis® Amodis® Amodis® Amodis® Amodis® Amodis® Amodis® Amodis® Amodis® Amodis® Amodis® Amodis® Amodis® Amodis® DOSAGE & ADMINISTRATION If not otherwise prescribed by the physician the following dosage schedule may be followed : 400–500 mg 2 hours before surgery; up to 3 further doses of 400–500 mg may be given every 8 hours for high-risk procedures